OncoKB¶
OncoKB matters when you need a focused oncology interpretation instead of general variant context. It is the source page to use when a workflow has already narrowed to an actionable somatic variant and you want evidence levels, oncogenicity framing, and therapy implications from a well-known cancer interpretation source.
In BioMCP, OncoKB is an explicit helper rather than an automatic section on every variant lookup. Use the variant oncokb command when you want the registration-gated production source. That helper requires ONCOKB_TOKEN, and BioMCP keeps the upstream TOKEN naming because OncoKB uses the same term in its own registration flow.
What BioMCP exposes¶
| Command | What BioMCP gets from this source | Integration note |
|---|---|---|
variant oncokb <id> |
Oncogenicity, treatment implications, and evidence levels | Explicit helper, not a default section on get variant |
Example commands¶
Returns an OncoKB interpretation for a common actionable melanoma variant.
Returns an OncoKB interpretation focused on evidence levels and treatment context.
Returns an OncoKB interpretation for a targeted oncology biomarker.
API access¶
Requires ONCOKB_TOKEN for the production OncoKB API. Configure it with the API Keys guide and register at OncoKB.
Official source¶
OncoKB is the official precision-oncology knowledgebase behind BioMCP's explicit OncoKB helper.