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ClinGen Criteria Specification Registry

ClinGen CSpec publishes versioned VCEP criteria specifications. BioMCP preserves source facts and exact stored provider captures; it does not evaluate ACMG criteria or produce classifications.

Select a document with either an exact full resource IRI returned by a manifest or a unique short version. The display version remains a separate provider fact and is not interchangeable with resource identity.

What BioMCP exposes

  • gene cspec <gene> lists full resource IRIs returned by the provider.
  • gene cspec <gene> --version <full-IRI-or-unique-short-version> retrieves one exact source document and binds its normalized gene, resource IRI, and specification ID to the capture.
  • gene cspec <gene> --capture-id <capture-id> pages that bound capture without another provider request.
  • Add --files to an exact version or capture selection to list bounded public attachment metadata without downloading files.
  • Typed MCP gene_cspec returns the manifest or bounded parsed capture pages. Its caller gene must match the captured binding.
  • Parsed pages include raw-byte provenance and a page-independent cspec-semantic-v1 digest; citations are deduplicated and capped at 32 per criterion.

Example commands

biomcp --json gene cspec ATM

List every available version IRI for ATM.

biomcp --json gene cspec ATM --version https://cspec.genome.network/cspec/SequenceVariantInterpretation/id/GN020/version/1.5.1
biomcp --json gene cspec ATM --version 1.5.1

Select one exact version or unique short version and retain its capture provenance.

biomcp gene cspec document <capture-id>
biomcp --json gene cspec PTEN --version <full-resource-iri> --files
biomcp --json gene cspec PTEN --capture-id <capture-id> --files

The document command streams the original local capture bytes without another provider request.

The attachment view exposes label, filename, declared media type and size, stable attachment ID, and a validated same-origin HTTPS URL. It accepts at most 100 linked files and fails the whole manifest instead of returning partial or truncated identifiers.

API access

No BioMCP API key required.

Official source