ChEMBL¶
ChEMBL matters when you want drug-target evidence that is still close to assay and mechanism data instead of a high-level summary alone. It is one of the fastest ways to explain why a drug is connected to a target and which indication context is public enough to surface in a lightweight lookup.
In BioMCP, ChEMBL mainly appears inside the drug targets section and the drug indications section. Those sections are mixed with OpenTargets, but ChEMBL is the part that contributes activity and mechanism context rather than a standalone ChEMBL search workflow.
What BioMCP exposes¶
| Command | What BioMCP gets from this source | Integration note |
|---|---|---|
get drug <name> targets |
Generic drug-target activity, mechanism, and target context | Mixed-source section: ChEMBL generic targets/mechanisms plus OpenTargets target context; CIViC may add a separate variant-target annotation line |
get drug <name> indications |
Drug indication context linked to known use areas | ChEMBL contributes indication enrichment alongside OpenTargets |
get cell-line <accession> chembl |
The ChEMBL cell line record for a Cellosaurus accession: ChEMBL ID, EFO ID, CLO ID, and the number of ChEMBL assays run on the line | Joined on cellosaurus_id. BioMCP lists no assays and no activity values |
Example commands¶
Returns a targets section with ChEMBL-backed activity and mechanism context.
Returns an indications section with ChEMBL-linked use-area context.
Returns a target-focused view for a kinase inhibitor with mechanism-oriented enrichment.
Returns the ChEMBL cell line record for MOLM-13 with its assay count. The section is asked for by name; get cell-line <accession> all leaves it out. It reads the release name and date from ChEMBL status.json at runtime and prints them with the CC BY-SA 3.0 attribution line.
API access¶
No BioMCP API key required.
Official source¶
ChEMBL is EMBL-EBI's public bioactivity database for drug-like molecules and targets.