CIViC¶
CIViC matters when you want clinically oriented cancer-variant evidence instead of a generic annotation alone. It is a good fit for workflows that need therapy relevance, disease context, or evidence assertions tied to specific molecular profiles and clinical interpretations.
In BioMCP, CIViC is exposed as section-gated enrichment rather than a full alternate entity system. The main entry points are get variant <id> civic, get gene <symbol> civic, get drug <name> civic, and disease workflows such as get disease <id> variants when you want CIViC-backed molecular profile context.
What BioMCP exposes¶
| Command | What BioMCP gets from this source | Integration note |
|---|---|---|
get variant <id> civic |
Variant-level CIViC evidence and assertions | Explicit opt-in section |
get gene <symbol> civic |
Gene-level CIViC evidence summary | Explicit opt-in section |
get drug <name> civic |
Therapy-context evidence for a drug | CIViC therapy evidence section |
get disease <id> civic |
Disease-context evidence and assertions | CIViC disease evidence section |
get disease <id> variants |
Disease-associated molecular profiles and variants | CIViC augments the disease variants workflow |
Example commands¶
Returns a CIViC section with variant evidence and assertion summaries.
Returns a gene-level CIViC evidence summary for BRAF.
Returns therapy-context CIViC evidence for the drug workflow.
Returns disease-context CIViC evidence and assertions for the disease record.
Returns disease-associated variants with CIViC-backed molecular profile context.
API access¶
No BioMCP API key required.
Official source¶
CIViC is the public clinical interpretation knowledgebase behind BioMCP's CIViC evidence sections.